Title: The Use of MTB for differential IHC panels including its use for best QA/QC Joelle Weaver MAOM, HTL(ASAP), Webinar from Indiana This one hour presentation will review basic quality control principles as applied to practice and methods of the performance of immunohistochemistry in the anatomic pathology laboratory. Diverse options are available to identify and utilize MTB control systems. Technical aspects such as how to select material and methods to construct MTB control blocks will be discussed. Literature discussion of the use of MTB blocks and control slides for immunohistochemistry will be introduced to support the discussion of this topic. Examples of the applications of the MTB controls to IHC panels, and testing efficiency will be provided.
Title: HistoQIP: What Is It and How do I Use It? Robert Lott, HTL(ASAP), Roche Tissue Diagnostics, Tucson, AZ For years, every section of the clinical laboratory has had proficiency testing (PT) and educational challenges/surveys, or some other means of objectively evaluating quality and accuracy of its testing except histology. With the introduction of HistoQIP, the Histology Quality Improvement Program, in 2004 the histology laboratory has its own CAP/NSH endorsed proficiency testing program. This workshop consists of a history and explanation of the program, but more importantly focuses on tips and suggestions on how to implement the program into the laboratory’s quality management plan (QMP) and improve daily quality using the materials and resources provided to participants enrolled in the program.
Title: Cancer Immunotherapy and PD-L1 Immunohistochemistry Testing Beth Sheppard, MBA, HT (ASCP), Roche Tissue Diagnostics, Tucson, AZ Cancer immunotherapy uses drugs that target immune system components to treat cancer. The PD-L1 protein is expressed on tumor cells and immune cells, and enables cancer cells to evade the host’s immune system via the apoptosis of T-cell clones, the inhibition of lymphocyte proliferation and T-cell cytokine secretion. PD-L1 expression on tumor cells and/or the tumor-immune infiltrate is part of the predictive model necessary for selecting patients predisposed to respond to monotherapy. Drug indications, both current and expected, are for Non-Small Cell Lung Cancer, Head and Neck Cancer, Bladder Cancer, Melanoma and Renal Cell Carcinoma. This workshop will discuss the mechanisms around blocking the PDL1 pathway, Immunohistochemistry antibodies and the different indications.
ASH & Region VII Summer Symposium
Fri, July 22 to Sun, July 24, 2016
Hilton Phoenix Airport
2435 S. 47th Street Phoenix, AZ 85034
Please register at: http://www.signupgenius.com/go/10c044facab23a1fe3-ashregion
ASH room rates are available with the promo code: RG7C for $85 plus tax. Don't wait, there are only a limited number of rooms and the rate expires June 21st.
Workshop registration will be available soon! Please check back for more details.
Sonora Quest Laboratories 1255 W. Washington Street Tempe, AZ 85281
8:00-11:30, Dionne Roberge Development and Commercialization of IVD Reagents for IHC What are we paying for when we purchase an in-vitro diagnostic (IVD) for clinical use? As consumers, we all want to know what we are paying for, and what does it mean for you? What kind of testing does a commercial vendor need to perform to market an IVD for use in (IHC)? What information should we expect the vendor to provide? The level of design quality used in the development of IHC reagents is a standard that all vendors must achieve, but how is it performed? With the rising costs of health care…
11:30-1:00, Lunch Together Lunch will be provided for members, so please join us
1:00-4:30, Jason Ramos IHC Principles and Troubleshooting This thorough review is designed to ensure all students have a concrete understanding of the biological principles behind IHC, how commercial IHC reagents are generated, and the implications of that knowledge on work in an IHC laboratory. Recent developments in the field of biology and immunology will be highlighted to build on knowledge attendees may already possess. Additionally, we will spend significant time on IHC troubleshooting, understanding where procedures go awry, how to identify a problem, and how to systematically go about correcting issues. All of the topics covered will be tied back to the IHC laboratory to improve basic knowledge and IHC skills. Sign up at: http://www.signupgenius.com/go/10c044facab23a1fe3-ashautumn
Rabies – the Arizona Experience 8:00-9:30am
Sharon Dial, DVM, PhD
Coccidioidomycosis (Valley Fever) – Arizona’s Disease 10:00-11:30am
Sharon Dial, DVM, PhD
Lunch 11:30- 12:30pm
General Membership Meeting 12:30-1:30pm
MSI Immunohistochemistry in Colon Cancer 1:30-3:00pm
Judy Pugh, M.D.
Standardization and Validation of IHC Testing 3:30-5:00pm
Beth Sheppard, MBA, HT (ASCP)